Thus, CHRNA3/5 variants may mediate airflow obstruction in both ever and never smokers. promotion info Supplementary Material Online Supplement: Click here to view. Acknowledgments The authors thank all the participants and research team members. The ARIC authors acknowledge Grace Chiu, Ph.D. (Westat, Research Triangle Park, NC) and Dick Howard (University of North Carolina at Chapel Hill, Chapel Hill, NC) for computational support and computer programming expertise. The LBC1936 authors thank the nurses and staff at the Wellcome Trust Clinical Research Facility, where subjects were tested and the genotyping was performed. Additional members of the SAPALDIA study, COPDGene study group, ECLIPSE, and the NETT Genetics Ancillary Study are listed in the online supplement.
The MESA authors thank the other investigators, the staff, and the participants of the MESA study for their valuable contributions. A full list of participating MESA investigators and institutions can be found at http://www.mesa-nhlbi.org. Sources of Funding J.B.W. is supported by a Young Clinical Scientist Award from the Flight Attendant Medical Research Institute. Research was conducted in part using data and resources from the Framingham Heart Study of the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) and Boston University School of Medicine. The analyses reflect intellectual input and resource development from the Framingham investigators participating in the SNP Health Association Resource (SHARe) project.
This work was partially supported by the NHLBI��s Framingham Heart Study (contract N01-HC-25195) and its contract with Affymetrix, Inc. for genotyping services (contract N02-HL-6-4278). A portion of this research used the Linux Cluster for Genetic Analysis (LinGA-II) funded by the Robert Dawson Evans Endowment of the Department of Medicine at Boston University School of Medicine and Boston Medical Center. The Atherosclerosis Risk in Communities Study is performed as a collaborative study supported by National Heart, Lung, and Blood Institute contracts (HHSN268201100005C, HHSN268201100006C, HHSN268201100007C, HHSN268201100008C, HHSN268201100009C, HHSN268201100010C, HHSN268201100011C, and HHSN268201100012C), R01HL087641, R01HL59367, and R01HL086694; National Human Genome Research Institute contract U01HG004402; and National Institutes of Health contract HHSN268200625226C. Infrastructure was partly supported by grant number UL1RR025005, a component of the National Institutes of Health and NIH Roadmap for Medical Research. Work was supported in part by the Division of Intramural Research, National Institute Drug_discovery of Environmental Health Sciences ZO1 ES43012.