Thicker layers show a negative magnetoresistance with extraordinary Hall effect constants up to 30 Omega T-1. Spin polarization transfer across the interface between Co2MnGa and GaAs is approximately 6.4% at 5 K in the current of a GaAs p-i-n diode even with compositional disorder at the interface. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3148298]“
“4-Aminobiphenyl (4-ABP), an aromatic amine is a major environmental carcinogen found mainly in cigarette smoke. It has been vastly implicated in mutagenesis and cancer development. In this study, commercially available human placental DNA was exposed to
4-ABP (1.3 mM) in presence of sodium nitroprusside (SNP; 8 mM) at 37 degrees C for 3 h. The
4-ABP + SNP-mediated structural changes in human DNA were studied by ultraviolet, Selleckchem GSK2879552 circular LY411575 dichroism and fluorescence spectroscopy, thermal melting profile, agarose gel electrophoresis, and nuclease S1 digestibility assay. Spectroscopical analysis and melting temperature studies suggest structural perturbations in the DNA as a result of modification. This might be due to generation of single-stranded regions and destabilization of hydrogen bonds. Modification was also visualized in agarose gel electrophoresis. Furthermore, nuclease S1 digestibility confirmed the generation of single strand breaks. Rabbits challenged with 4-ABP-SNP-modified human DNA-induced high-titer immunogen-specific antibodies, which showed Cross-reaction with modified/unmodified DNA bases and ss-DNA in competitive inhibition assay. The immunogen specificity of induced antibodies against 4-ABP-SNP-modified human DNA was further confirmed in gel retardation assay. It may be concluded
HDAC inhibitor that induction of anti-modified DNA antibodies could be due to perturbation in the DNA structure and its subsequent recognition by immunoregulatory cells as a foreign molecule. (c) 2012 Wiley Periodicals, Inc. Environ Toxicol 29: 568-576, 2014.”
“Objectives: This study examined the link between coping and quality of life among patients with gastrointestinal (GI) cancer. Two hypotheses were tested. The active-personality hypothesis states that quality of life is associated with the predominant use of primary control coping (PCC) in general. The situational-flexibility hypothesis states that quality of life is related to flexible deployment of PCC and secondary control coping (SCC) according to situational controllability. Methods: Participants were 180 Chinese adult patients diagnosed with colon or liver cancer. Their perceived controllability of stressors, coping, and quality of life were compared with those of a sex-and age-matched community sample.