The prevalence found in this study corroborates the results of the literature, which indicate a high consumption of
medication by children. It is also important to understand that medication use appears to be associated to low-income, as it is subsidized ABT737 by the government. Moreover, children aged 0 to 14 years, in general, are in a phase in life when health problems that require the use of medications should consider indication and age restrictions. The use of medications, in addition to being an indicator of health problems, also reflects social inequalities and deficiencies, quality of the healthcare system, regulations related to medications in the country, medical education, cultural habits, and the pharmaceutical market composition, among others factors. The epidemiological reality of medication use should be considered by healthcare professionals and managers to create educational programs. In this sense, the nursing work process BEZ235 starts with drug prescription in primary care, and may involve studies of pharmacoepidemiology and pharmacovigilance in order to understand the consumption profile, resulting in knowledge that will allow interventions aimed at promoting rational use of medications. Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMG-Process n. CDS-APQ-02522-11). The authors declare no conflicts of interest. The authors would
like to thank the interviewers (Alex, Lays, and Guilherme), the interviewed families, and Prof. Dr. Delba. “
“The approach of patent ductus arteriosus (PDA) in Fossariinae the neonatal period has been widely discussed in the literature, both regarding the best time to detect it, as well as the conduct to be used in the presence of DA, particularly in preterm newborns (PNBs) of low birth weight, considering its implications for the evolution of these newborns. While the DA is an essential structure during the intrauterine period, responsible for the deviation of the pulmonary circulation to the aorta and maintaining
the fetal systemic blood flow, its persistence after birth may trigger a series of events, culminating with heart failure.1 Particularly in infants with birth weight (BW) below 1,000 g, patent ductus arteriosus (PDA) with hemodynamic effects may be associated with greater morbimortality,2 resulting in higher risks of heart failure, duration of mechanical ventilation, bronchopulmonary dysplasia (BPD),3 intraventricular hemorrhage (IVH),4 and necrotizing enterocolitis (NEC).5 However, a considerable percentage of PDAs will close spontaneously,6 and 7 or may remain patent without causing significant symptoms.7 Consequently, early start of the treatment may unnecessarily expose NBs to prostaglandin inhibitors or surgical ductus ligation, which are associated with adverse effects.