The aim of the study was to investigate the intuitive use of different laryngeal airway devices by first-year medical students. Therefore, the insertion of a LMA-Classic and a LMA-Fastrach was compared in a resuscitation model. The effects of a short teaching programme and the improvement on the laypersons’ performance after these minimal theoretical instructions were examined. Moreover, the retention of skills was reviewed to evaluate Inhibitors,research,lifescience,medical long-term effects. Methods Subjects; Ethical

Considerations Subjects embodied were 139 first year medical students. They were tested at the very beginning of their studies, during their first two weeks at the medical faculty of the University of Aachen. All subjects were informed that their performance would be evaluated and used for scientific purposes. No personal data was collected. Furthermore, no influence on the health of the subjects was expected. Therefore, the local research ethical committee of the RWTH Aachen waived to obtain informed consent from each person. None of the subjects were prompted or prepared in any way prior to the study. Equipment Inhibitors,research,lifescience,medical The laryngeal airway devices tested were the LMA-Classic™ and the LMA-Fastrach™ (LMA Vertriebs-GmbH, Germany). Both instruments were

applied in size 4. To standardize cuff inflation volume the recommended maximum was used. Via a ventilatory tube the trachea was connected with a volumeter on which the tidal volume could be read after Inhibitors,research,lifescience,medical positioning the airway tool. The exact time from first handling the device to correct insertion was buy PD98059 recorded with Inhibitors,research,lifescience,medical a laboratory stop watch (Junghans, Germany). The airway trainer (Laerdal, Norway) was used as a model for insertion of the two airway devices. The airway trainer was placed on a table and therefore easily accessable. Study protocol After randomization, the students were assigned to insert either the LMA-Classic or the LMA-Fastrach. Three physicians skilled in providing and teaching Advanced Life Support (ALS) (certified Instructors of the European Resuscitation Council, ERC) were present during the whole performance Inhibitors,research,lifescience,medical of

each student and recorded time until the particular device was meant to be placed Cell press correctly. All tested persons were instructed with the same standardized sentence: “This patient is unconscious and not breathing. The device in front of you may help to keep the airway open. Please insert the instrument as you consider it correctly”. The test ended when the subject confirmed the correct position in his opinion. Afterwards the cuff was inflated by the observer according to the manufacturer’s suggestions. Tidal volume was measured with a volumeter by ventilating with an ambu bag. A tidal volume under 150 ml was considered as insufficient. Beside measuring the time to correct placement of the laryngeal airway, number of attempts and initial tidal volume were documented. Air leakage was identified by audible sound during ventilation.