Only 6 patients showed a large hearing change. This happened early during follow-up, with relatively stable hearing after this.
CONCLUSION: Hearing will deteriorate in some intracanalicular
vestibular schwannomas, regardless of tumor growth. Hearing deterioration, if on a large scale, most likely occurs early Ferrostatin-1 supplier in follow-up. The present results using conservative management in these tumors appear similar to those reported for stereotactic radiotherapy or microsurgery.”
“BACKGROUND: Vertebral hemangiomas (VH) are the most common lesions of the vertebral column.
OBJECT: To evaluate the role of intraoperative ethanol embolization, surgical decompression, and instrumented fusion in VH presenting with myelopathy.
METHODS: This is was a prospective study of single-level symptomatic VH with cord compression. Exclusions were as follows: pathological fractures, deformity, or multilevel pathologies. Surgery consisted of intraoperative bilateral pedicular absolute alcohol injection and laminectomy at the level of pathology
followed by a short-segment instrumented fusion using pedicle screws.
RESULTS: Ten patients (mean, 26.8 +/- 18.11; range, 10-68 years; 8 females) were treated with use of this technique. Clinical features included myelopathy with motor and sensory involvement in all (4 paraplegic), sphincter involvement (8), and severe local pain (5). The preoperative American Spinal Injury Association (ASIA) scores were A (3), Fedratinib mouse B (1), and C (6). All had pan vertebral body VH with severe cord compression. The mean surgical time was 102 +/- 22 minutes; average blood, 296 +/- 90.82 mL. Mean amount of absolute alcohol injected was 12.6 +/- 4.7 mL (1 requiring 25 mL). Immediate embolization
was achieved in all patients allowing laminectomy and soft-tissue hemangioma removal. Postsurgery, all patients showed improvement (sphincters improved in 4) at a follow-up ranging 12 to 26 months (transient neurological deterioration in 1). Postsurgery ASIA scores were D (5) and E (5) at last follow-up. Two patients showed evidence of bone sclerosis on follow-up CT scans at 1.2 and 1.5 years.
CONCLUSION: This procedure seems to VX-770 research buy be a safe, efficient method to treat VH with severe cord compression. It seems to serve the purpose of providing embolization, cord decompression, and rigid fusion at the same sitting.”
“BACKGROUND: Intracranial pressure is routinely monitored in patients with severe traumatic brain injury (TBI). Patients with TBI sometimes develop hydrocephalus, requiring permanent cerebrospinal fluid (CSF) diversion.
OBJECTIVE: To quantify the need for permanent CSF diversion in patients with TBI.
METHODS: Patients who received a ventriculostomy after TBI between June 2007 and July 2008 were identified, and their medical records were abstracted to a database.
RESULTS: Sixteen of 71 patients (22.5%) receiving a ventriculostomy required a ventriculoperitoneal or ventriculoatrial shunt before discharge from the hospital.