The evidence's reliability was determined to be in the range of low to moderate certainty. Legume consumption at a higher level was connected with reduced mortality from all causes and stroke, but no correlation was found for mortality from cardiovascular disease, coronary artery disease, and cancer deaths. Legumes are advocated for increased consumption, as supported by these research findings.
Although a considerable amount of data exists on the correlation between diet and cardiovascular mortality, research on long-term food group intake, with the potential for cumulative effects on long-term cardiovascular health, is comparatively scant. This study, therefore, investigated the connection between the long-term use of 10 food groups and death due to cardiovascular disease. Our systematic search of Medline, Embase, Scopus, CINAHL, and Web of Science databases spanned a period up to January 2022. Twenty-two studies, each with 70,273 participants exhibiting cardiovascular mortality, were eventually included in the analysis, out of the original 5,318 studies. The random effects model was used to estimate the summary hazard ratios and corresponding 95% confidence intervals. The study found a significant reduction in cardiovascular mortality from the prolonged high intake of whole grains (HR 0.87; 95% CI 0.80-0.95; P = 0.0001), fruits and vegetables (HR 0.72; 95% CI 0.61-0.85; P < 0.00001), and nuts (HR 0.73; 95% CI 0.66-0.81; P < 0.000001). Every 10 grams more of whole grains consumed daily was associated with a 4% lower risk of cardiovascular mortality; conversely, every 10-gram rise in red/processed meat intake per day was linked to an 18% higher risk of cardiovascular mortality. Innate mucosal immunity Relative to the lowest consumption group, individuals in the highest category of red and processed meat intake experienced a heightened risk of cardiovascular mortality (Hazard Ratio 1.23; 95% Confidence Interval 1.09 to 1.39; P = 0.0006). A high consumption of dairy products and legumes did not appear to be related to cardiovascular mortality (HR 111; 95% CI 092, 134; P = 028) and (HR 086; 95% CI 053, 138; P = 053), respectively. The dose-response assessment showed that each 10-gram rise in weekly legume intake corresponded to a 0.5% decrease in cardiovascular mortality. Our findings indicate that a persistent high intake of whole grains, vegetables, fruits, and nuts, in conjunction with a low intake of red and processed meats, is associated with a decrease in cardiovascular mortality. A deeper understanding of the long-term effects of legumes on cardiovascular mortality is desirable. read more The study, registered with PROSPERO, holds the identifier CRD42020214679.
The popularity of plant-based dietary approaches has increased considerably in recent years, and they have been identified as an effective dietary strategy to help in the prevention of chronic conditions. Variably, the classifications of PBDs are subject to the kind of diet involved. Certain PBDs, owing to their rich vitamin, mineral, antioxidant, and fiber content, are considered healthful, whereas those high in simple sugars and saturated fat are deemed unhealthful. A PBD's protective outcome against disease is substantially contingent on the specific category into which it's classified. Metabolic syndrome (MetS), a condition marked by high plasma triglycerides, low HDL cholesterol, impaired glucose metabolism, elevated blood pressure, and increased concentrations of inflammatory markers, is a significant risk factor for both heart disease and diabetes. Consequently, a dietary approach centered on plant-based foods could prove suitable for people diagnosed with Metabolic Syndrome. A study of the differing effects of various plant-based diets – vegan, lacto-vegetarian, lacto-ovo-vegetarian, and pescatarian – is presented, emphasizing the specific role of dietary components in weight management, dyslipidemia prevention, insulin resistance reduction, hypertension control, and the prevention of chronic, low-grade inflammation.
Grain-derived carbohydrates are prominently found in bread throughout the world. High intakes of refined grains, with their low dietary fiber content and high glycemic index, are frequently observed in those with an increased likelihood of type 2 diabetes mellitus (T2DM) and other chronic health problems. Henceforth, alterations to the ingredients in the production of bread may influence the health status of the people. A systematic review explored the influence of regular reformulated bread consumption on glucose regulation among healthy adults, individuals with heightened cardiometabolic risk, or those with diagnosed type 2 diabetes. Employing MEDLINE, Embase, Web of Science, and the Cochrane Central Register of Controlled Trials, a search for relevant literature was implemented. Adult participants (healthy, at risk of cardiometabolic issues, or diagnosed with type 2 diabetes) involved in a two-week bread intervention were evaluated for glycemic outcomes—fasting blood glucose, fasting insulin, HOMA-IR, HbA1c, and postprandial glucose responses. A random-effects model, utilizing generic inverse variance weights, analyzed the pooled data and the findings were expressed as mean differences (MD) or standardized mean differences (SMD) between treatments, presented with 95% confidence intervals. 22 research studies, having a total of 1037 participants, qualified under the specified inclusion criteria. When substituting standard bread with reformulated intervention bread, fasting blood glucose was lower (MD -0.21 mmol/L; 95% CI -0.38, -0.03; I2 = 88%, moderate certainty of evidence). However, there were no differences in fasting insulin (MD -1.59 pmol/L; 95% CI -5.78, 2.59; I2 = 38%, moderate certainty of evidence), HOMA-IR (MD -0.09; 95% CI -0.35, 0.23; I2 = 60%, moderate certainty of evidence), HbA1c (MD -0.14; 95% CI -0.39, 0.10; I2 = 56%, very low certainty of evidence), or postprandial glucose response (SMD -0.46; 95% CI -1.28, 0.36; I2 = 74%, low certainty of evidence). The subgroup analyses indicated an advantageous impact on fasting blood glucose, particularly for those diagnosed with T2DM, although this conclusion carries a degree of uncertainty. In adults, particularly those with type 2 diabetes, our study demonstrates a favorable impact of reformulated breads high in dietary fiber, whole grains, and/or functional ingredients on fasting blood glucose levels. CRD42020205458 constitutes this trial's registration number in the PROSPERO database.
The public increasingly views sourdough fermentation—a process driven by the combined action of lactic bacteria and yeasts—as a natural method for achieving nutritional advantages; yet, the scientific community hasn't fully confirmed these purported benefits. To comprehensively analyze the clinical data, this study performed a systematic review of sourdough bread's effects on health. Up to February 2022, a dual database search (The Lens and PubMed) was undertaken to locate relevant bibliographic entries. Eligible studies were determined to be randomized controlled trials involving adults, including those in poor health, who received either sourdough or yeast bread, respectively. Out of a pool of 573 articles examined, 25 clinical trials fulfilled the necessary inclusion criteria. medical mycology Across twenty-five clinical trials, a collective 542 individuals participated. The retrieved studies examined glucose response (N = 15), appetite (N = 3), gastrointestinal markers (N = 5), and cardiovascular markers (N = 2), encompassing several significant outcomes. In evaluating the health advantages of sourdough against other breads, a clear consensus proves elusive. This uncertainty stems from the interplay of several variables, including the microbial communities in the sourdough, the fermentation techniques used, the type of cereal, and the flour type, all of which can affect the nutritional value of the bread. Despite this, studies employing particular yeast strains and fermentation procedures demonstrated notable enhancements in parameters linked to blood sugar control, fullness, and digestive ease following bread consumption. Data analysis reveals sourdough's potential for producing a range of functional foods; however, its complex and dynamic microbial community demands more standardization for determining its clinical health advantages.
The issue of food insecurity disproportionately impacts Hispanic/Latinx households in the United States, with young children being especially vulnerable. Although studies have linked food insecurity to poor health outcomes in young children, a significant gap exists in understanding the social drivers and associated risk factors of food insecurity specifically among Hispanic/Latinx households with children under three, a vulnerable demographic. In line with the Socio-Ecological Model (SEM), this narrative review identified factors affecting food insecurity among Hispanic/Latinx families with children less than three years. To identify relevant literature, PubMed and four other search engines were employed in the search. Inclusion criteria were set by selecting English-language publications between November 1996 and May 2022 that explored food insecurity issues specifically within Hispanic/Latinx households and their young children, under the age of three. Exclusions were applied to articles not performed in the U.S., and/or if those articles concentrated on refugees or temporary migrant workers. Data encompassing objective, setting, population, study design, food insecurity assessments, and outcomes were extracted from each of the 27 final articles (n=27). Each article's evidence was also scrutinized for its strength. A range of factors, from individual (intergenerational poverty, education, acculturation, language, etc.) to interpersonal (household composition, social support, cultural practices), organizational (interagency collaboration, organizational policies), community (food environment, stigma, etc.), and public policy/societal (nutrition assistance programs, benefit cliffs, etc.), were identified as significantly impacting the food security of this group. In summary, the majority of articles received a medium to high quality rating for evidence strength, and their subject matter often concentrated on individual or policy-related factors.