DXM may have additional or synergistic effects with MXF.”
“Background: The stair-climbing test is commonly used in the preoperative evaluation of lung resection candidates,

but it is difficult to standardize and provides little physiologic information on the performance. Objective: To verify the association between the altitude and the VO(2peak) measured during the stair-climbing test. Methods: 109 consecutive candidates for lung resection performed a symptom-limited stair-climbing test with direct breath-by-breath measurement of VO(2peak) by a portable gas analyzer. Stepwise logistic regression and selleckchem bootstrap analyses were used to verify the association of several perioperative variables buy INCB28060 with a VO(2peak) <15 ml/kg/min. Subsequently, multiple regression analysis was also performed to develop an equation to estimate VO(2peak) from stair-climbing parameters and other patient-related variables. Results: 56% of patients climbing <14 m had a VO(2peak) <15 ml/kg/min, whereas 98% of those climbing >22 m had a VO(2peak) >15 ml/kg/min. The altitude reached at stair-climbing test resulted in the only significant predictor of a VO(2peak) <15 ml/kg/min after logistic regression analysis. Multiple regression analysis yielded an equation to estimate VO(2peak) factoring altitude (p < 0.0001), speed of

ascent (p = 0.005) and body mass index (p = 0.0008). Conclusions: There was an association between altitude and VO(2peak) measured during the stair-climbing test. https://www.selleckchem.com/products/xmu-mp-1.html Most of the patients climbing more than 22 m are able to generate high values of VO(2peak) and can proceed to surgery without any additional tests. All others need to be referred for a formal cardiopulmonary exercise test. In addition, we were able to generate an equation to estimate VO(2peak), which could assist in streamlining the preoperative workup and could be used across different settings to standardize this test. Copyright (C) 2010 S. Karger AG, Basel”
“Endoscopic stenting is a relatively new technique for the treatment of post sleeve gastrectomy

complications. Partially covered stents are used in this method to minimise the risk of migration but they are associated with difficulties with removal. Patients requiring emergency stenting following sleeve gastrectomy underwent insertion of a partially covered metallic stent. One month later, if the stent was not easily removable, a fully covered overlapping stent was inserted and the patient was readmitted 2 weeks later for removal of both stents. Four patients required stenting following sleeve gastrectomy leaks, and one patient required stenting for a stricture. In these cases, a ‘stent in a stent’ technique was used for removal. This technique allows the safe removal of partially covered stents inserted following sleeve gastrectomy complications.